Idiopathic pulmonary-renal syndrome

The clinical challenge of an underestimated condition

  • Jorge de Jesús Cantillo Turbay Hospital El Tunal ESE (Bogotá, Colombia)
  • Jorge Ernesto Andrés Díaz Ruíz Hospital El Tunal ESE (Bogotá, Colombia)
  • José Santiago Valderrama Sánchez Hospital El Tunal ESE (Bogotá, Colombia)
  • Emir Ancízar Ortiz Ibarra Hospital Universitario Clínica San Rafael (Bogotá, Colombia)

Abstract

The specific pulmonary-renal syndrome term (PRS) denotes simultaneous and continuously pulmonary hemorrhage (PH) and glomerulonephritis (GN). Therefore, the specific PRS implies a much more restrictive range of etiological possibilities and the most frequent is the small vessel vasculitides (SVVsVPV). As a consequence, it is known at present that the coexistence of the two affections, it means GN and PH, results from a series of illnesses with different underlying pathogenic mechanisms. The diagnosis of PRS is established by a combination of clinical presentation, serologic results and histological findings evaluated in an adequate clinical context. In the majority of patients with PH and GN, it is necessary to make a renal biopsy and final diagnostic test in the majority of cases; and with great value for the prognosis and treatment.

The objectives of the treatment in PRS include: To remove the circulating antibodies, to stop the autoantibodies production; and to remove any antigen that stimulates the antibodies production. We reported six PRS cases by vasculitic disorder in adult patients.

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Author Biographies

Jorge de Jesús Cantillo Turbay, Hospital El Tunal ESE (Bogotá, Colombia)

Jefe Servicio de Nefrología y Diálisis, Hospital El Tunal E.S.E. Servicio de Terapia Renal

Jorge Ernesto Andrés Díaz Ruíz, Hospital El Tunal ESE (Bogotá, Colombia)

Jefe Servicio de Terapia Renal

José Santiago Valderrama Sánchez, Hospital El Tunal ESE (Bogotá, Colombia)

Servicio de Terapia Renal

Emir Ancízar Ortiz Ibarra, Hospital Universitario Clínica San Rafael (Bogotá, Colombia)

Residente II de Nefrología. Hospital Universitario Clínica San Rafael, Bogotá D.C.

Published
2006-03-01
How to Cite
Cantillo Turbay, J. de J., Díaz Ruíz, J. E. A., Valderrama Sánchez, J. S., & Ortiz Ibarra, E. A. (2006). Idiopathic pulmonary-renal syndrome: The clinical challenge of an underestimated condition. Acta Medica Colombiana, 31(1), 31-39. Retrieved from https://actamedicacolombiana.com/ojs/index.php/actamed/article/view/2459
Section
Case Reports

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