History of Henoch-Schönlein purpura

Abstract

Henoch-Schonlein purpura (HSP) is defined as a primary systemic vasculitis of small vessels characterized by predominantly IgA immune deposits on the walls of the capillaries, venules, and arteriales. It typically involves skin, intestines, and glomeruli and is associated with arthritis and arthralgia. Robert Willan (1757-1812), the founder of modern dermatology, was the first to clearly describe vasculitis and its significance. This article analyzes the fundamental history of HPS.