Nefritis tubulointersticial aguda por ácido zoledrónico

Julián Andrés Ocampo Alzate; Lina Marcela Aguirre-Hernández; José Manuel Ustariz-Duran; Joaquín Roberto Rodelo-Ceballos; Alejandro Román-González

doi:10.36104/amc.2025.4719

Zoledronic acid-induced acute tubulointerstitial nephritis

Julián Andrés Ocampo Alzate Universidad de Antioquía (Medellín, Colombia)
Lina Marcela Aguirre-Hernández Departamento de Nefrología; Hospital Universitario San Vicente Fundación https://orcid.org/0000-0002-5717-3776
José Manuel Ustariz-Duran Departamento de Nefrología; Hospital Universitario San Vicente Fundación https://orcid.org/0000-0002-3914-0356
Joaquín Roberto Rodelo-Ceballos Departamento de Nefrología; Hospital Universitario San Vicente Fundación https://orcid.org/0000-0002-9533-6214
Alejandro Román-González Departamento de Endocrinología; Universidad de Antioquia https://orcid.org/0000-0001-5942-1035

DOI: https://doi.org/10.36104/amc.2025.4719

Abstract

Intravenous bisphosphonates are drugs with nephrotoxic potential. This drugs may be associated with acute tubular necrosis and focal segmental glomerulosclerosis. We present the case of a 79-year-old woman who, after the intravenous application of zoledronic acid for the treatment of osteoporosis, developed acute tubulointerstitial nephritis that caused acute kidney injury requiring renal replacement therapy, with a good response to treatment with glucocorticoids.

PDF (Español (España))

Published

2025-08-23

How to Cite

Ocampo Alzate, J. A., Aguirre-Hernández, L. M., Ustariz-Duran, J. M., Rodelo-Ceballos, J. R., & Román-González, A. (2025). Zoledronic acid-induced acute tubulointerstitial nephritis. Acta Médica Colombiana, 50(4). https://doi.org/10.36104/amc.2025.4719

Download Citation

Issue

Vol. 50 No. 4 (2025): REVISTA ACTA MEDICA COLOMBIANA - DIGITAL

Section

Case Reports

This work is licensed under a Creative Commons Attribution 4.0 International License.

Acta Medica Colombiana uses the CC-BY 4.0 license. Authors retain all rights over their work.