Early warning scores to identify the risk of clinical worsening or death in patients hospitalized for COVID-19
Abstract
Background: identifying patients at risk for negative outcomes is key for performing a timely triage and adapting the care intensity for patients with COVID-19. Early warning scores are rules that alert to the risk of adverse outcomes during hospitalization. We sought to validate the modified NEWS, NEWS-2 and COVID-19 Severity Index (CSI).
Methods: a prospective observational multicenter study of patients hospitalized for COVID-19 at three quaternary care hospitals in Bogotá, Colombia, between April and November 2020. The operating characteristics and areas under the ROC curve were calculated.
Results: 711 patients were included, in whom the AUC for death was 0.68, 0.58 and 0.68, and for ICU admission was 0.61, 0.63 and 0.66 for mNEWS, NEWS-2 and CSI, respectively. The CSI had the greatest sensitivity for ICU admission or death (87.6 and 90.0%) and NEWS-2 had the greatest specificity (76.8 and 75.5%).
Conclusions: the three early warning scores had a low to moderate performance in predicting ICU admission or death in patients hospitalized for COVID-19.
Metrics
Copyright (c) 2022 John Jaime Sprockel Díaz, Edna Carolina Araque Parra, Juan José Chaves Cabezas, Hellen Cárdenas Rodríguez, Ruddy Paola Montoya Rumpf, Eliana Angarita González, María Paula Carrillo Ayerbe, Victoria Elena Coral Zúñiga, Iván Santiago Acuña Cortes, Sebastián Tabares Rodríguez
This work is licensed under a Creative Commons Attribution 4.0 International License.
Acta Medica Colombiana uses the CC-BY 4.0 license. Authors retain all rights over their work.
