Li-Fraumeni Syndrome

Metachronous presentation of soft-tissue sarcoma, heart sarcoma and gastric cancer

  • Jesús Solier Insuasty-Enríquez Universidad Industrial de Santander (Bucaramanga, Colombia)
  • Valeria Ortega Apraez Universidad autónoma de bucaramanga
  • Eduardo Javier Arias-Quiroz Hospital Internacional de Colombia (Piedecuesta, Colombia)
  • Martha Liliana Alarcón-Tarazona Hospital Internacional de Colombia (Piedecuesta, Colombia)
  • Carlos Alberto Calderón-Cortés Hospital Internacional de Colombia (Piedecuesta, Colombia)
DOI: https://doi.org/10.36104/amc.2022.2198

Abstract

Li-Fraumeni syndrome is an autosomal hereditary dominant disorder with cancer predisposition, it´s associated with abnormalities in the tumor protein p53 (TP53) gene, which is manifested by a wide range of malignancies that appear at an early age. We present a case of a young adult with this diagnosis, and we described the therapeutic perspectives that are in research.

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Author Biography

Jesús Solier Insuasty-Enríquez, Universidad Industrial de Santander (Bucaramanga, Colombia)

InternistaOncólogo Clínico. Director del Grupo de Investigación Germina UIS. Profesor Departamento de Medicina Interna UIS. Unidad de Oncología Hospital Universitario de Santander. Insuasty Oncología e investigación SAS(IOIS)

Published
2021-09-09
How to Cite
Insuasty-Enríquez, J. S., Ortega Apraez, V., Arias-Quiroz, E. J., Alarcón-Tarazona, M. L., & Calderón-Cortés, C. A. (2021). Li-Fraumeni Syndrome: Metachronous presentation of soft-tissue sarcoma, heart sarcoma and gastric cancer. Acta Médica Colombiana, 47(1). https://doi.org/10.36104/amc.2022.2198
Issue
Vol. 47 No. 1 (2022): ACTA MÉDICA COLOMBIANA - DIGITAL
Section
Case Reports

Copyright (c) 2021 Valeria Ortega Apraez

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