Heparin and insulin in the management of acute hypertriglyceridemic pancreatitis

Case report

  • Juan Pablo Camargo Mendoza Hospital de Kennedy (Bogotá, Colombia)
  • Daniel Efrén Rodríguez Ariza Hospital de Kennedy (Bogotá, Colombia)
  • Jhonny Steven Bustos Calvo Hospital de Kennedy (Bogotá, Colombia)

Abstract

Hypertriglyceridemic pancreatitis (HTGP) is the third cause of acute pancreatitis in most studies, with a triglyceride (TG) risk value of more than 1,000 mg/dL. The pathophysiological mechanism involves triglyceride hydrolysis by pancreatic lipase and the release of fatty acids which cause damage by producing free radicals. The reduction of TGs below 500 mg/dL is the treatment goal, based on increased lipoprotein lipase activity and chylomicron degradation. We present the case of a patient with HTGP with an adequate response to concomitant insulin and heparin therapy

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Author Biographies

Juan Pablo Camargo Mendoza, Hospital de Kennedy (Bogotá, Colombia)
Médico Internista, Neumólogo Clínico, Epidemiólogo Clínico, Magister en hipertensión pulmonar
Daniel Efrén Rodríguez Ariza, Hospital de Kennedy (Bogotá, Colombia)
Médico Internista, Magister en Epidemiología, Unidad de Cuidado Intensivo Hospital de Kennedy
Published
2019-12-20
How to Cite
Camargo Mendoza, J. P., Rodríguez Ariza, D. E., & Bustos Calvo, J. S. (2019). Heparin and insulin in the management of acute hypertriglyceridemic pancreatitis: Case report. Acta Médica Colombiana, 45(1). https://doi.org/10.36104/amc.2020.1491
Section
Case Reports