Characterization of kidney transplant patients with expanded criteria donors

Abstract

Introduction: renal transplantation is the treatment of choice for patients with chronic kidney disease; however, the number of donors is insufficient and waiting lists grow exponentially every year. Transplantation with expanded criteria donors benefits a significant number of patients, improving their survival when comparing them with those who remain on dialysis. The objective of this study is to describe the characteristics of the transplanted patients with the expanded criteria donors and their renal function at the first and third year of the transplant.

Methods: an observational descriptive study was performed. Patients over 18 years of age transplanted with an expanded criteria donor between 2007 and 2015 were chosen.

Recipients were 59.5 years old (37-79), waiting list time of 22.4 months (2.6-77.8), dialysis time of 4.5 years (0.5-18.4). The donor"(TM)s age was 61 years (50-73). Graft survival at one year was 88.9% and at three years was 80%. 11.1% of the patients presented acute cellular rejection at one year and the average glomerular filtration rate at the first and third year was 58.4 mL / min / 1.73m2.

Conclusion: Patients transplanted with an expanded criteria donor have a good function of the renal graft at three years, with graft and patient survival, similar to that reported with a donor with standard criteria

Method: a descriptive study was carried out. Patients older than 18 years were transplanted from expanded criteria donors between 2007 and 2015.

Results: Out of a total of 227 patients analyzed, 18 were transplanted from expanded criteria donors. The recipients had a mean age of 59.3 years, waiting list time of 29.9 months, mean time on dialysis of 7 years. The average age of the donor was 61 years. Graft survival per year was 88.9% and at 3 years 80%. 11.1% of the patients presented acute cellular rejection at one year, and the average glomerular filtration rate at the first and third year was 58.4 ml / min / 1.73m2.

Conclusion: Patients transplanted from expanded criteria donors have a good renal graft function at 3 years, with graft and patient survival similar to that reported with standard criteria deceased donors.