Prevalence of metabolic syndrome in patients infected with HIV

Using ATP III and IDF criteria

Abstract

Background: metabolic syndrome is a set of abnormalities related to one another that are associated with the development of diseases like diabetes, hypertension and dyslipidemia. In Colombia there are no published studies regarding the prevalence of metabolic syndrome in people with HIV infection.

Methods: we carried out a cross-sectional observational study, the sample was composed by patients in consultation with HIV-AIDS in a hospital in third level, during the period March-April 2008; took into account patients over 18, who were not hospitalized during the past month.

Results: the final sample was comprised of 137 patients, of whom 82.5% were men and 17.5% women, aged between 19 and 65 years (average age 39.7 ± 9.64 years), body mass index averaged 23.8 Kg/mt2 ± 3.13 and 78.4% were receiving antiretroviral therapy.

The prevalence of metabolic syndrome according to the criteria of ATPIII was 15.4% (95% 9.8% 22.6%). According to the criteria of the IDF prevalence of metabolic syndrome was 21.3% (95% 14.43% - 28.20%); There was no correlation between the use of antiretroviral therapy and the presence of metabolic syndrome, was found a high prevalence of lipid disorders in patients with metabolic syndrome.

Conclusions: further studies are needed in order to define the role of metabolic complications in the progression of the disease and the prognosis of patients, laying emphasis on its role as a cardiovascular risk factor.