New micronebulizer device with continuous control of the inspired oxygen fraction (“CONTROLizer”)
Mauricio Orozco-Levi, Alba Ramírez-Sarmiento, Angela Espitia, Maria Fernanda Saavedra, Melissa Mogollón, Diana Isabel Cáceres, Rubén Duarte, Norma Serrano, Leonardo Rodriguez, Eugenio Sarmiento, Camilo Pizarro, Joaquim Gea
One of the most common techniques of respiratory treatment is the nebulization of medications to be administered by inhalation using oxygen as a propellant, which in turn is considered a drug that can generate adverse effects related to the dosage. The objective of this research was to design, develop and analyze a dual micronebulization system with precise control of FIO2.
Methods: a virtual model and a functional prototype were designed, constructed and evaluated following the bioengineering methodology of a new micronebulizer device with FIO2 control. The functioning of the device and its impact on healthy volunteers and hospitalized patients were evaluated through specific psychometric scales.
Results: a device that integrates a micronebulizer (container), which allows to nebulize physiological saline or solutions of diverse drugs based on the pressurization of a propellant gas (air or oxygen) along with a mechanism of adjustment of the fraction of inspired oxygen (minimum 21%, maximum 99%), was conceptualized, designed and constructed. The limits (maximum and minimum) of recommended flow to generate the aerosol are 6-8 l / min. In no case of use complications occurred.
Conclusions: CONTROLizer is a dual and non-invasive integrated device for the micronebulization of respiratory solutions and continuous control of the fraction of inspired oxygen. Due to its qualities and functioning, the device was perceived as adequate and safe to be applied in healthy individuals and patients admitted in both intensive care and conventional hospitalization rooms
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